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Cassiopeia Matchups

CassiopeiaMatchups

Master every matchup: stats-driven builds, runes, skills, and laning insights, combined with Master-Tier tips and community contributions.

Patch 15.18
MatchupThreatGamesWRGold @ 15Gold DiffTips
Champion Portrait of Sylas
Sylas
Easy
13556%+245+719Punish him early by weaving auto-attacks between your E casts. Your W will not stop the second part of his E. If you are able to land your R, immediately follow it with W before using your Q and E.

Skill Priority

Cassiopeia E Icon
E
Twin Fang
Cassiopeia lets loose an attack that deals increased damage to Poisoned targets and heals her for a percentage of the damage dealt. If the target dies from this attack, Cassiopeia regains Mana.
Cassiopeia Q Icon
Q
Noxious Blast
Cassiopeia blasts an area with Poison after a brief delay, granting her increased Move Speed if she hits an enemy champion.
Cassiopeia W Icon
W
Miasma
Cassiopeia releases several clouds of poison, slowing, grounding, and lightly damaging enemies that pass through them. Grounded enemies cannot use Movement abilities.
55.9% WR
127 Matches

Summoner Spells

Summoner Spell 1Summoner Spell 2
54.5% WR
55 Matches

Skill Order

Cassiopeia Q Icon
Noxious Blast
Cassiopeia blasts an area with Poison after a brief delay, granting her increased Move Speed if she hits an enemy champion.
2
8
10
12
13
Cassiopeia W Icon
Miasma
Cassiopeia releases several clouds of poison, slowing, grounding, and lightly damaging enemies that pass through them. Grounded enemies cannot use Movement abilities.
4
14
15
Cassiopeia E Icon
Twin Fang
Cassiopeia lets loose an attack that deals increased damage to Poisoned targets and heals her for a percentage of the damage dealt. If the target dies from this attack, Cassiopeia regains Mana.
1
3
5
7
9
Cassiopeia R Icon
Petrifying Gaze
Cassiopeia releases a swirl of magical energy from her eyes, stunning any enemies in front of her that are facing her and slowing any others with their back turned.
6
11
16

Cassiopeia vs Sylas Runes

Press the Attack
Lethal Tempo
Fleet Footwork
Conqueror
Absorb Life
Triumph
Presence of Mind
Legend: Alacrity
Legend: Haste
Legend: Bloodline
Coup de Grace
Cut Down
Last Stand
Axiom Arcanist
Manaflow Band
Nimbus Cloak
Transcendence
Celerity
Absolute Focus
Scorch
Waterwalking
Gathering Storm
53.1% WR98 Matches
Adaptive Force
Attack Speed
Ability Haste
Adaptive Force
Armor
Magic Resist
Health
Armor
Magic Resist

Starting Items

Item 1056Item 2003Item 3340
66.7% WR
24 Matches

Core Items

Item 3040Item 6657Item 3116
78.6% WR
14 Matches

4th Item Options

Item 6653
64.3% WR14 Matches
Item 3116
41.7% WR12 Matches
Item 6657
40.0% WR10 Matches

5th Item Options

Item 3116
66.7% WR6 Matches
Item 3089
66.7% WR3 Matches
Item 3040

6th Item Options

Item 3040
100.0% WR1 Matches
Item 6653
100.0% WR1 Matches
Item 3116

Laning Phase (@15 min)

Cassiopeia Damage
8,368
Sylas Damage
6,797
Gold Diff+245
CS Diff+20
XP Diff+276
Ally Ganks1.70
Enemy Ganks2.20

End of Game

Cassiopeia Damage
26,023
Sylas Damage
22,319
Total Gold Diff+719
Total CS Diff+31

Split Push

Cassiopeia Dmg to Turrets
2,919
Sylas Dmg to Turrets
2,886
Champion Portrait of Syndra
Syndra
Very Hard
10140%-236-1401She has a significant range advantage and can poke you easily with her Q. She lacks mobility and is therefore vulnerable to ganks. Save your W for when you can close the gap or to support your jungler. Capitalize on the window when her E is on cooldown.
Champion Portrait of Ryze
Ryze
Easy
8256%+187+251This is one of your best matchups. Your W makes it much easier to land your Q. When he looks to use his W, you can counter with your R, as he will be facing you.
Champion Portrait of Yasuo
Yasuo
Very Hard
7946%-281-627
💬 No tips yet — Be the first to add a tip!
Champion Portrait of Hwei
Hwei
Very Hard
7841%-159-692
💬 No tips yet — Be the first to add a tip!
Champion Portrait of Orianna
Orianna
Even
7856%-7-10This is one of your most difficult matchups. She will outrange you. Focus on farming as best you can and wait for your jungler to gank. You can take extended trades with Conqueror if you feel she may run out of mana or is behind in items.
Champion Portrait of Yone
Yone
Easy
7854%+322-109
💬 No tips yet — Be the first to add a tip!
Champion Portrait of Vladimir
Vladimir
Very Hard
7742%-183-1154Take Ignite. Weave auto-attacks between your E casts during the early laning phase. Your poison damage and Ignite will continue to do damage while he is in his W.
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